Clinical and immunological efficiency of bacteriophage in technique of delayed prescribing of antibiotics in patients with acute post-viral rhinosinusitis

Topicality: Acute Rhinosinusitis can be characterised as acute bacterial rhinosinusitis just in about 0,5 - 2% of the number viral one and only such patients need prescription antibiotics. At same time, antibacterial therapy is prescribed from 54% to 77% cases Rhinosinusitis. To reduce unreasonable prescriptions, strategy delayed prescribing antibioticsis forward-looking one. Aim: evaluate level IgА sIgA with post-viral RS estimate clinical immunological efficiency polyvalent bacteriophage technique antibiotics comparison receiving standard APVRS therapy. Material methods: 155 adult participated trial who were given either or addition In conjunction treatment, levels evaluated their dynamics was undertaken. Evaluation criteria: decrease intensity disease symptoms accordance MSS scale system during each visit 1st visit, antibiotic frequency, changes serum secretory levels. Results discussion: The use bacteriophagein rhinosinusitisas a part ensures clinically significant, faster regression typical rhinosinusitis: rhinorrhea, nasal congestion post-nasal drip control group (p<0.05). Positive symptomatology followed by fair increase (p<0.005), before treatment group. statistically significant difference between intervention indicators associated fairly higher (by 20%) rate Conclusion: safe effective medication for additional intended improve systemic local immunity inclusion into regimen could recommended